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#475 – Demis Hassabis: Future of AI, Simulating Reality, Physics and Video Games

#475 – Demis Hassabis: Future of AI, Simulating Reality, Physics and Video Games

Lex Fridman Podcast
Jul 23, 2025 2h 35m
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About this episode

<p>Demis Hassabis is the CEO of Google DeepMind and Nobel Prize winner for his groundbreaking work in protein structure prediction using AI.<br /> Thank you for listening ❤ Check out our sponsors: <a href="https://lexfridman.com/sponsors/ep475-sc">https://lexfridman.com/sponsors/ep475-sc</a><br /> See below for timestamps, transcript, and to give feedback, submit questions, contact Lex, etc.</p> <p><b>Transcript:</b><br /> <a href="https://lexfridman.com/demis-hassabis-2-transcript">https://lexfridman.com/demis-hassabis-2-transcript</a></p> <p><b>CONTACT LEX:</b><br /> <b>Feedback</b> &#8211; give feedback to Lex: <a href="https://lexfridman.com/survey">https://lexfridman.com/survey</a><br /> <b>AMA</b> &#8211; submit questions, videos or call-in: <a href="https://lexfridman.com/ama">https://lexfridman.com/ama</a><br /> <b>Hiring</b> &#8211; join our team: <a href="https://lexfridman.com/hiring">https://lexfridman.com/hiring</a><br /> <b>Other</b> &#8211; other ways to get in touch: <a href="https://lexfridman.com/contact">https://lexfridman.com/contact</a></p> <p><b>EPISODE LINKS:</b><br /> Demis&#8217;s X: <a href="https://x.com/demishassabis">https://x.com/demishassabis</a><br /> DeepMind&#8217;s X: <a href="https://x.com/GoogleDeepMind">https://x.com/GoogleDeepMind</a><br /> DeepMind&#8217;s Instagram: <a href="https://instagram.com/GoogleDeepMind">https://instagram.com/GoogleDeepMind</a><br /> DeepMind&#8217;s Website: <a href="https://deepmind.google/">https://deepmind.google/</a><br /> Gemini&#8217;s Website: <a href="https://gemini.google.com/">https://gemini.google.com/</a><br /> Isomorphic Labs: <a href="https://isomorphiclabs.com/">https://isomorphiclabs.com/</a><br /> The MANIAC (book): <a href="https://amzn.to/4lOXJ81">https://amzn.to/4lOXJ81</a><br /> Life Ascending (book): <a href="https://amzn.to/3AhUP7z">https://amzn.to/3AhUP7z</a></p> <p><b>SPONSORS:</b><br /> To support this podcast, check out our sponsors &#38; get discounts:<br /> <b>Hampton:</b> Community for high-growth founders and CEOs.<br /> Go to <a href="https://lexfridman.com/s/hampton-ep475-sc">https://joinhampton.com/lex</a><br /> <b>Fin:</b> AI agent for customer service.<br /> Go to <a href="https://lexfridman.com/s/fin-ep475-sc">https://fin.ai/lex</a><br /> <b>Shopify:</b> Sell stuff online.<br /> Go to <a href="https://lexfridman.com/s/shopify-ep475-sc">https://shopify.com/lex</a><br /> <b>LMNT:</b> Zero-sugar electrolyte drink mix.<br /> Go to <a href="https://lexfridman.com/s/lmnt-ep475-sc">https://drinkLMNT.com/lex</a><br /> <b>AG1:</b> All-in-one daily nutrition drink.<br /> Go to <a href="https://lexfridman.com/s/ag1-ep475-sc">https://drinkag1.com/lex</a></p> <p><b>OUTLINE:</b><br /> (00:00) &#8211; Introduction<br /> (00:29) &#8211; Sponsors, Comments, and Reflections<br /> (08:40) &#8211; Learnable patterns in nature<br /> (12:22) &#8211; Computation and P vs NP<br /> (21:00) &#8211; Veo 3 and understanding reality<br /> (25:24) &#8211; Video games<br /> (37:26) &#8211; AlphaEvolve<br /> (43:27) &#8211; AI research<br /> (47:51) &#8211; Simulating a biological organism<br /> (52:34) &#8211; Origin of life<br /> (58:49) &#8211; Path to AGI<br /> (1:09:35) &#8211; Scaling laws<br /> (1:12:51) &#8211; Compute<br /> (1:15:38) &#8211; Future of energy<br /> (1:19:34) &#8211; Human nature<br /> (1:24:28) &#8211; Google and the race to AGI<br /> (1:42:27) &#8211; Competition and AI talent<br /> (1:49:01) &#8211; Future of programming<br /> (1:55:27) &#8211; John von Neumann<br /> (2:04:41) &#8211; p(doom)<br /> (2:09:24) &#8211; Humanity<br /> (2:12:30) &#8211; Consciousness and quantum computation<br /> (2:18:40) &#8211; David Foster Wallace<br /> (2:25:54) &#8211; Education and research</p> <p><b>PODCAST LINKS:</b><br /> &#8211; Podcast Website: <a href="https://lexfridman.com/podcast">https://lexfridman.com/podcast</a><br /> &#8211; Apple Podcasts: <a href="https://apple.co/2lwqZIr">https://apple.co/2lwqZIr</a><br /> &#8211; Spotify: <a href="https://spoti.fi/2nEwCF8">https://spoti.fi/2nEwCF8</a><br /> &#8211; RSS: <a href="https://lexfridman.com/feed/podcast/">https://lexfridman.com/feed/podcast/</a><br /> &#8211; Podcast Playlist: <a href="https://www.youtube.com/playlist?list=PLrAXtmErZgOdP_8GztsuKi9nrraNbKKp4">https://www.youtube.com/playlist?list=PLrAXtmErZgOdP_8GztsuKi9nrraNbKKp4</a><br /> &#8211; Clips Channel: <a href="https://www.youtube.com/lexclips">https://www.youtube.com/lexclips</a></p>

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