#189 – David Sinclair: Extending the Human Lifespan Beyond 100 Years

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<p>David Sinclair is a geneticist at Harvard and author of Lifespan. Please support this podcast by checking out our sponsors:<br /> &#8211; <b>Onnit</b>: <a href="https://lexfridman.com/onnit">https://lexfridman.com/onnit</a> to get up to 10% off<br /> &#8211; <b>Clear</b>: <a href="https://clearme.com/lexpod">https://clearme.com/lexpod</a> and use code LexPod to get 2 months free<br /> &#8211; <b>National Instruments (NI)</b>: <a href="https://www.ni.com/perspectives">https://www.ni.com/perspectives</a><br /> &#8211; <b>SimpliSafe</b>: <a href="https://simplisafe.com/lex">https://simplisafe.com/lex</a> and use code LEX to get a free security camera<br /> &#8211; <b>Linode</b>: <a href="https://linode.com/lex">https://linode.com/lex</a> to get $100 free credit</p> <p><b>EPISODE LINKS:</b><br /> David&#8217;s Twitter: <a href="https://twitter.com/davidasinclair">https://twitter.com/davidasinclair</a><br /> David&#8217;s Website: <a href="https://lifespanbook.com">https://lifespanbook.com</a></p> <p><b>PODCAST INFO:</b><br /> Podcast website: <a href="https://lexfridman.com/podcast">https://lexfridman.com/podcast</a><br /> Apple Podcasts: <a href="https://apple.co/2lwqZIr">https://apple.co/2lwqZIr</a><br /> Spotify: <a href="https://spoti.fi/2nEwCF8">https://spoti.fi/2nEwCF8</a><br /> RSS: <a href="https://lexfridman.com/feed/podcast/">https://lexfridman.com/feed/podcast/</a><br /> YouTube Full Episodes: <a href="https://youtube.com/lexfridman">https://youtube.com/lexfridman</a><br /> YouTube Clips: <a href="https://youtube.com/lexclips">https://youtube.com/lexclips</a></p> <p><b>SUPPORT &#38; CONNECT:</b><br /> &#8211; Check out the sponsors above, it&#8217;s the best way to support this podcast<br /> &#8211; Support on Patreon: <a href="https://www.patreon.com/lexfridman">https://www.patreon.com/lexfridman</a><br /> &#8211; Twitter: <a href="https://twitter.com/lexfridman">https://twitter.com/lexfridman</a><br /> &#8211; Instagram: <a href="https://www.instagram.com/lexfridman">https://www.instagram.com/lexfridman</a><br /> &#8211; LinkedIn: <a href="https://www.linkedin.com/in/lexfridman">https://www.linkedin.com/in/lexfridman</a><br /> &#8211; Facebook: <a href="https://www.facebook.com/lexfridman">https://www.facebook.com/lexfridman</a><br /> &#8211; Medium: <a href="https://medium.com/@lexfridman">https://medium.com/@lexfridman</a></p> <p><b>OUTLINE:</b><br /> Here&#8217;s the timestamps for the episode. On some podcast players you should be able to click the timestamp to jump to that time.<br /> (00:00) &#8211; Introduction<br /> (09:34) &#8211; Staying young at heart<br /> (13:31) &#8211; Bringing people back to life<br /> (19:05) &#8211; Wearables and tracking health data<br /> (28:18) &#8211; How to solve aging<br /> (38:23) &#8211; Why do we age?<br /> (43:50) &#8211; Genetic reset switch that reverses aging<br /> (46:20) &#8211; AI in biology<br /> (48:52) &#8211; Health data<br /> (56:58) &#8211; Fasting<br /> (1:04:29) &#8211; Diet<br /> (1:12:41) &#8211; Exercise<br /> (1:18:01) &#8211; Sleep<br /> (1:26:29) &#8211; Data<br /> (1:32:00) &#8211; Extending lifespan<br /> (1:34:42) &#8211; Immortality<br /> (1:40:28) &#8211; Denial of death<br /> (1:43:45) &#8211; Meaning of life without death</p>